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Our group research bacterial mobile division and is particularly aiming to represent a ‘bottom up biology’ in synthetic cells which can autonomously divide. Our most important desire lies in mobile division, chromatin construction, and spatial control.

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Deposition and atomic drive microscopy of unique phthalocyanine polymers concerning nanofabricated electrodes

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Experimental stage diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,

Due to the fact 2000 he moved to one-molecule biophysics and nanobiology, with study from DNA supercoiling scientific tests of nucleosomes and DNA repair proteins to DNA translocation by means of nanopores. Just lately his investigate has centered on studying cell division with germs on chip, although his best desire is during the direction of recognizing synthetic cells.

He also uncovered time to jot down many guides, mail Just about forty thousand tweets and guide An effective analysis team at Delft College of Technology. ‘It doesn’t feel like do the job’, he suggests. ‘I’m just terribly curious.’

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There was one particular dilemma while — we did not observe any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule stage, conducting polymers have been really not this kind of great conductors, which was rather disappointing. We So broadened our watch to try to discover much more promising molecules.

An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes

Character Physics many thanks the anonymous reviewers for his or her contribution to the peer overview of the perform.

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2004, discovery of new physics in translocation of DNA by nanopores; initial experimental analyze of ions conduction in nanofluidic channels; very first electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization in the mechanical Attributes of double-stranded RNA; and initial solitary-molecule study of DNA translocation by a restriction-modification enzyme.