New Step by Step Map For ceesdekker
Rotary motion of DNA rotors on nanopores. Leading row: Uncooked video clip of your Cy5 channel of each and every rotor. Middle row: corresponding one-particle localization effects of equally finishes with the DNA rotors. The place of the present frame is marked as orange and blue dots, plus the trajectory of the 10 frames in advance of the current body is shown as reliable strains.Human Rad51 filaments on double- and one-stranded DNA: correlating typical and irregular sorts with recombination perform.
Multicolor imaging of the bacterial nucleoid and mobile division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
Your browser isn’t supported any more. Update it to obtain the best YouTube working experience and our most current attributes. Find out more
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is usually that these elements jointly make up a residing program. The trick of explained life, I feel, lies in the interactions, the interplay of Those people molecules. The large dilemma in regards to the origin of life continues to be unanswered. How did we at any time evolve from easy molecules in the extremely intricate units we see right now? We do not know. I want to work on these kinds of major, open inquiries.’
Nanopores stand for a sublime and multipurpose Software to evaluate solitary molecules. We exploration novel detection modes with stable-condition nanopores and also several solutions to evaluate proteins with nanopores. Assignments encompass the next:
2003, demonstrated the first biosensors built out of a carbon nanotube; fixed the framework and mechanism of DNA restore proteins; and discovery of a new technique for fabricating good-condition nanopores for DNA translocation
Dekker began his research on one carbon nanotubes in 1993 when he create a new line of investigate to review electrical transport by single natural and organic molecules involving nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was obtained in the collaboration Using the team of Nobel laureate Richard Smalley. STM and cees dekker nanolithography strategies were accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with remarkable Bodily Attributes.
Because 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. A lot more recently his exploration has focused on finding out chromatin structure and mobile division with bacteria on chip, when he can also be seeking to in the end Establish synthetic cells from The underside up.
Cees Dekker is Distinguished University Professor at TU Delft. Trained as being a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His current research focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in particular SMC motor protein; and (iii) developing a dwelling artificial cell from lifeless molecules. Dekker is surely an elected member from the KNAW and fellow towards the APS and the IOP.
Publisher’s Observe Springer Character remains neutral with regard to jurisdictional promises in released maps and institutional affiliations.
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design and style in 2005. (nl)